Dynamic light scattering (DLS) determines the size distribution profile of molecules or nanoparticles in solution by quantifying dynamic fluctuations in the intensity of scattered light from moving particles. The fluctuations are directly related to the rate of diffusion of the molecule through the solvent, which is related in turn to the particles' hydrodynamic radius. Via the Stocks-Einstein equation, the size can be determined. Light scattering based techniques have also been extensively used in characterizing molecular interactions such as protein aggregation, oligomerization and the kinetics of self-assembly. 
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