The incorporation of PEG-lipid leading liposomes helps to remain drug for longer time periods in the blood circulation, which has been widely recognized as one of the most successful strategies to improve the delivery of therapeutic molecules. At present, the most popular way to produce long-circulating liposomes is to attach hydrophilic polymer PEG covalently to the outer surface. Steric stabilization results from the local surface concentration of highly hydrated PEG groups which attracts a water shell around the vehicles as Steric barrier. https://www.cd-bioparticle...

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