Based on over 10 years of experience in neuroscience, Creative Biolabs has successfully established a mitochondrial stress detection platform. With our advanced platform and professional team, Creative Biolabs provides customized mitochondrial stress assay services to global customers to solve the challenges of your mitochondrial projects. https://neuros.creative-bi...
Creative Biolabs has long-term devoted to the development and application of neuronal models for neuroscience research. Based on our years of research, now we can provide novel human iPSC derived neuronal cell culture models for our clients all over the world. https://neuros.creative-bi...
With a high reputation in the oligonucleotide synthesis field, Creative Biolabs has rich experience in creating a custom siRNA using online design tools and extensive synthesis options for specific applications. Today, our team has built a series of worry-free customizations for siRNA synthesis based on clients' sequences or sequences we have designed as clients' request. The synthesized oligos can meet all demands, including siRNA for different species, specific splice variants, and delivered forms. https://www.creative-biola...
With advanced technology and specialized infrastructure, Creative Biolabs offers a full range of custom miRNA inhibitor services as synthetic oligonucleotides and vector-based expression clones for biotechnology, pharmaceutical, and related industries. Meanwhile, we'd like to exactly develop miRNA modulation tools that clients need and design customized inhibitors available for miRNAs not listed in the general database. https://www.creative-biola...
CAR-T cell therapy has made great achievements in the past decade, while conventional CAR-T cell therapy also has some obstacles to overcome, such as the CRS and ICANS toxicity, and the expensive and complex manufacturing process. The in-vivo CAR-T cell engineering by nanoparticles carrying CAR genes and gene-editing tools has shown potential breakthroughs in overcoming the above obstacles of traditional CAR-T cell therapies. Therefore, there is more urgent to develop safe and simple in-vivo CAR-T cell engineering solutions. https://www.creative-biola...
With the help of world first-class technology platforms and skillful scientific teams in the field of antibody discovery and immunotherapy, Creative Biolabs now provides reliable and high-quality MHC/peptide complex production service for TCR-like antibody discovery. https://www.creative-biola...
Creative Biolabs is the leading custom service provider that has extensive experience in various antibody production and engineering fields. As the leading custom service provider specializing in antibody production and engineering fields, Creative Biolabs has been keeping a close eye on the development of the epidemic situation and accelerating the development of monkeypox antibodies. Please feel free to contact us to learn more products and custom production. Learn more, https://monkeypox.creative...
With years of experience, Creative Biolabs can offer an extensive range of recombinant proteins and peptides including orthopoxviruses family, parapoxviruses family, molluscipoxviruses family, yatapoxviruses family, capripoxviruses family, suipoxviruses family, leporipoxviruses family and avipoxviruses family. Learn more, https://monkeypox.creative...
As the leading custom service provider, Creative Biolabs has been keeping a close eye on the development of the epidemic situation and accelerating the development of detection kits. Creative Biolabs provides Monkeypox virus nucleic acid detection kits and ELISA kits. Learn more, https://monkeypox.creative...
Monkeypox virus (MPXV) which causes monkeypox in humans and other animals is a type of double-stranded DNA virus. It is a member of the family Poxviridae and the genus Orthopoxvirus. And it is one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. Monkeypox can infect a diverse array of mammalian species according to taxonomy, however the actual native host is unknown. Learn more, https://monkeypox.creative...
For cell solutions, microfluidic is trying to renewal the research methods and has made certain achievements.Nowadays, microfluidic chip has been applied in many cell solutions Based on the mature technical system and professional scientists, Creative Biolabs has launched comprehensive microfluidic chip development services for cell solutions. Learn more, https://microfluidics.crea...
Microfluidic chips offer various possibilities for performing biochemical assays. These range from the separation of biomolecules, in particular of small molecules, proteins, and nucleic acids, to the preparation and analysis of biofluids, such as blood, sweat, and other biological fluids. Learn more, https://microfluidics.crea...
Microfluidic chip has proven its important role in many areas of practical applications, such as clinical diagnosis, drug development, and cell biology. Microfluidic chips consist of a series of linking microchannels through which different types of fluids are injected and controlled, allowing the regulation of many parameters at a single-cell level. Learn more, https://microfluidics.crea...
In recent years, low-cost nucleic acid solutions on microfluidic chips have been developed, which would become a more valuable platform and one of the most common tools in the biomedical field. Creative Biolabs is a leader in microfluidic chip development. With years of experience and advanced microfluidic platforms, our scientists are pleased to offer the best-qualified outcomes to meet our customers' specific requirements for the development of microfluidic chips. Learn more, https://microfluidics.crea...
Creative Biolabs provides a wide variety of antibodies relevant to cellular marker or cell surface antigens of various species. We offer comprehensive suite of anti-cellular marker antibodies to advance your research and maximize your project success. Learn more, https://neutab.creative-bi...
Creative Biolabs is dedicated to providing comprehensive support and services based on neutralizing antibodies for our clients. Here, we offer the protocol for Micro-neutralization (MN) Assay, aiming to provide clients with a detailed understanding of the experiment's procedures and workflow. This will assist clients in making informed experimental plans and decisions. Learn more, https://neutab.creative-bi...
Antibodies are Y-shaped molecules made up of heavy and light chains that each has a variable and a constant region. The variable regions of both the heavy and light chains are responsible for antigen binding. The constant region of the heavy chain determines the class to which the antibody belongs. Antibodies with the same isotype have the same constant regions. Learn more, https://neutab.creative-bi...
Recombinant antibodies (rAbs) have been widely applied in the field of biological research, diagnosis and therapy based on their unique advantages. Without immunization and screening process, antibody gene sequence is cloned and expressed in vitro via cellular expression system. Currently, mammalian cells are the preferred system for large-scale production as the rAbs produced are biochemically similar to human forms. Learn more, https://neutab.creative-bi...
As a leading supplier in the field of microarrays, Creative Biolabs is committed to designing and developing various effective biological microarray products for research. Our microarray test platform provides convenient and rapidly sialic acid binding analyzation with proteins, virus or other microorganism to help our global customers conduct relevant research and reduce research costs. Learn more, https://www.creative-biola...
Glycoengineering is increasingly recognized as an important strategy in the development of new biopharmaceuticals with optimized half-life, antigenicity, and efficacy. With years of experience and advanced technologies, Creative Biolabs has proposed different genetic strategies to circumvent issues like heterogeneity, nonhuman glycans in different glycoprotein production systems. Learn more, https://www.creative-biola...
Therapeutic glycoproteins have become the fastest growing fields in the pharmaceutical industry. With first-in-class technologies and experienced scientists, Creative Biolabs has successfully developed versatile glycoprotein production platforms. Based on these cutting-edge platforms, we can provide our worldwide clients with the largest and most diverse portfolio of standard or custom therapeutic glycoprotein services. Learn more, https://www.creative-biola...
Thin-layer chromatography (TLC) is a planar chromatographic technique extensively used as a relatively rapid and straightforward analytical technique for glycan analysis based on their relative hydrophobicity. Creative Biolabs has explored an efficient strategy for the analysis of not only neutral monosaccharide and oligosaccharide, but also for acidic monosaccharides, disaccharides, and oligosaccharides. We are more than happy to share our experience to help our customers in carbohydrate analysis. Learn more, https://www.creative-biola...
Bacterial proteomics is the large-scale study of proteins produced by bacteria. It involves techniques like mass spectrometry and bioinformatics to analyze protein expression, function, and interactions, shedding light on bacterial physiology, pathogenesis, and potential therapeutic targets, ultimately enhancing our understanding of microbial life.
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Phospholipids are main components of the cellular membrane with characteristics of excellent biocompatibility and especial amphiphilicity. When introduced into aqueous milieu, the amphiphilic phospholipids self-assembly generates different structures depending on their properties, for example, bilayers, micelles, and liposomes. The molecule structure of phospholipid consists of a hydrophilic head group and hydrophobic acyl chains linked to the alcohol.
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DSPE-PEG is a biocompatible polymer used in drug delivery systems. It improves solubility and stability, facilitating targeted therapy. This compound enhances the pharmacokinetics of pharmaceuticals, making it a vital component in nanomedicine and biopharmaceutical applications. Its unique properties enable efficient cellular uptake and reduced toxicity.
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Multi-strain probiotics consist of various beneficial bacteria strains that work synergistically to enhance gut health. These probiotics can improve digestion, boost immunity, and restore the natural balance of gut flora. By incorporating diverse strains, they offer a broader range of health benefits and support overall well-being. https://live-biotherapeuti...
LBPs must overcome physiological challenges in the gut and their metabolic functions play a crucial role in conquering these challenges. Bacterial metabolomics is the study of small molecules produced by bacteria, providing insights into their metabolic processes. This approach aids in understanding bacterial growth, interactions, and responses to environmental changes, ultimately contributing to advancements in microbiology, disease prevention, and biotechnological applications. https://live-biotherapeuti...
Inflammatory bowel disease (IBD) is a chronic and non-specific inflammatory disease of the intestine, including Crohn's disease (CD) and ulcerative colitis (UC), and its etiology remains unclear. Probiotics for Crohn’s disease may help enhance gut health by balancing intestinal flora. These beneficial bacteria can potentially reduce inflammation, alleviate symptoms, and improve the quality of life for patients. However, it’s essential to consult healthcare professionals before incorporating probiotics into a treatment plan. https://live-biotherapeuti...
How to test complement activation?
Over the past two decades, highly specific monoclonal antibodies have been generated that recognize only neoepitopes exposed in the activation product, which enables direct capture of complement activation products by ELISA or high-capacity immunosorbents without the interference of the nonactivated component. A number of complement activation products have been tested by this method, including the classical pathway (C1rs-C1 inhibitors, C4d and C4bc), alternative pathways (Ba, Bb, and C3bBЬP), C3 (C3a, iC3b/C3bc, and C3d) and terminal reactions sequence (C5a and sC5b-9).
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The total complement activity contributes to a comprehensive understanding of the activation status of the complement system to better define disease occurrence, severity, and response to treatment. Therefore, the total complement activity test has very important clinical value in the diagnosis and subsequent treatment of complement-related diseases. The most common methods of total complement activity tests include hemolysis assays, liposome lysis, and enzyme-linked immunosorbent assays (ELISAs). https://www.creative-biola...