Rational protein design is a great challenge to our understanding of protein structure and physical chemistry. It has been widely used in numerous fields, including synthetic biology. Rational design is the most significant approach of protein engineering based on site-directed mutagenesis. The strategy is based on the relating structure to function, frequently via molecular modeling techniques. Rational design requires the knowledge of the amino acid sequence, 3D structure and function of the target protein. This method provides controllable amino acid sequence changes such as insertion, deletion, substitution, exchange of secondary structural elements, exchange of the entire domain, or fusion of enzymes to create new proteins.
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AI Guided Enzyme Design is a process that uses artificial intelligence and machine learning to design and improve enzymes. It combines computational methods, machine learning algorithms, and experimental validation for precise results. The use of AI in enzyme design process allows for a more efficient and quicker design of new enzymes, as well as the enhancement of existing ones. It can predict the structure and function of enzymes based on their sequence, removing a lot of the guesswork from enzyme design. It serves a crucial role in modern enzyme design, with the potential to create enzymes with novel functions that could not be achieved using traditional methods. For more information, please visit at: https://www.biosynsis.com/...

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